Genetically determined enzyme and transporter deficiencies may cause hereditary intolerance to common dietary sugars. ViennaLab assays identify the most frequent genetic variations responsible for sugar intolerance.

Sugar Intolerance

• Lactose intolerance is a frequent autosomal recessive condition causing diarrhea, nausea and flatulence. The disease is strongly associated with genetic variants regulating the expression of the lactase (LCT) gene.
• Hereditary fructose intolerance is an autosomal recessive disorder caused by variants of the aldolase B (ALDOB) gene. Affected subjects suffer from abdominal pain, vomiting, hypoglycemia, and unless fructose-containing food is strictly avoided may even die from organ damage.
• ViennaLab assays are available for the detection of two LCT and four ALDOB genetic variants.