VIENNALAB - Established innovations in diagnostics

Oral anticoagulants like coumarin are commonly used to prevent and treat stroke. Genetic variants influence drug efficacy potentially leading to life-threatening wrong dosage. ViennaLab assays identify the most relevant genetic variations influencing coumarin anticoagulation therapy.

Anticoagulation Therapy Response

  • Coumarins (vitamin K antagonists) are highly effective in prevention and treatment of stroke, myocardial infarction and venous thromboembolism.
  • Correct coumarin dosage is indispensable to avoid life-threatening bleeding (overdose) or lack of therapeutic effect (insufficient dose).
  • Variations in the genes responsible for coumarin antagonism of vitamin K and coumarin turnover influence drug affinity and thus its therapeutic effect.
  • Identification of genetic variants thus allows life-saving adjustment of coumarin anticoagulation therapy.

Product Details

PGX-Thrombo StripAssay® ref4-730
VKORC1 -1639G>A RealFast™ Assay ref7-190 7-193